Use Of HRT Hormone Replacement Therapy

Hormonal imbalance can be due to natural conditions such as menopause or other conditions. For hormone therapy to slow down heart disease, a woman’s blood vessels Hormone Replacement Therapy Madison need to be clean and healthy, Hodis says. If the vessels are already sick, which can happen once women are well past menopause, estrogen won’t help much.

At the age of 65, their risk of suffering a heart attack is equal to that of men. The spectrum and intensity of symptoms that women experience during perimenopause and menopause vary widely. The symptoms are the result of the effect of decreased circulating estrogen levels on various organ systems. Hypothalamic-mediated vasomotor instability, which leads to hot flashes, sweating, and palpitations, is the most common manifestation of menopause. Hormone therapy involves the administration of synthetic estrogen and progestin. HT is designed to replace a woman’s strenuous hormone levels and thus alleviate her menopausal symptoms.

The risk of breast cancer increases in conjunction with the use of hormones for thin women, but not for heavy women. Adipose tissue is the main source of endogenous estrogen after menopause, and circulating estrogen levels are significantly increased in obese postmenopausal women. Therefore, exogenous estrogen may have a lower impact on estrogen availability in heavy women than in thin women.

The risk was higher for women who took hormones and decreased over time after the hormones were stopped. Compound bioidentical HT or natural HT approved by the Food and Drug Administration as a safer alternative. However, there is no clear evidence that custom CBHT formulas are safer or more effective than FDA-approved HT products. Doctors may want to use personalized formulas for those patients who do not tolerate standard HTN. In the mid-1970s, studies showed that postmenopausal women who used only estrogen therapy had a significantly increased risk of endometrial cancer.

However, if someone has had a hysterectomy, they can take estrogen on their own. Of the two hormones, estrogen and progesterone, progesterone likely produces a higher risk of breast cancer than estrogen actually does. Estrogen with or without progestin is the most effective treatment for hot flashes and is available in oral and patch dosage forms. Symptoms of natural menopause are treated with a combination of estrogen and progestin; Progestin balances estrogen and reduces the risk of uterine cancer. Because women who have had a hysterectomy no longer have a uterus, they can only take estrogen to relieve the symptoms of artificial menopause. Women who experience early menopause for any reason should take HRT until at least the age of 45 to prevent diseases such as osteoporosis, heart disease, and dementia.

The duration of treatment of these hormones should not be more than a few years, and close monitoring is required. If the woman has mild symptoms of menopause, the benefits and harms of these hormones should be taught. The pharmacist should consult with the prescribing doctor about the exact remedy and dosage, and at the same time examine the patient’s register of drugs. Nurses should be very aware of the signs of adverse events and closely monitor them on subsequent visits to alert the doctor to concerns. This interprofessional team approach will achieve the best results with HRT. Hormone replacement therapy is the therapeutic replacement of estrogen with or without progestin (a drug similar to progesterone).

Women are more susceptible than men, and the low estrogen levels of menopause can accelerate progressive bone loss, especially in the first 5 years after menopause. This situation predisposes postmenopausal women to the development of osteoporosis and osteoporosis-related fractures. A 50-year-old woman has a lifetime risk of 40% of suffering a fracture that usually occurs in the femoral neck, vertebrae, or distal forearm.

Hormone replacement therapy may be an effective treatment for menopausal symptoms, but some types of HRT can increase the risk of breast cancer. Preventive Services Task Force recommends not using combined estrogen and progestin for the primary prevention of chronic disease in most postmenopausal women with the uterus intact. The statement also adds that estrogen alone has no net benefit for the primary prevention of chronic disease for most postmenopausal women who have undergone a hysterectomy. Contrasting new findings from a GHI memory sub-study showed that older women who took combined hormone therapy had twice the rate of dementia, including Alzheimer’s disease, compared to women who did not. The study, which is part of the Women’s Health Initiative Memory Study, found an increased risk of dementia in women aged 65 years and older who took combined HT.